The East Hawaii Cultural Center (EHCC) is a cultural center in Hilo, Hawaii, that has regular art exhibits and holds workshops and classes. Administered by the East Hawaii Cultural Council, an umbrella group of local arts organizations, the Center is housed in a historic former police station facing Kalakaua Park.

'Imiloa Astronomy Center weaves together Hawaii's cultural heritage with today‚s newest astronomy findings into a compelling story of star exploration. The center incorporates both Hawaiian and English languages to enhance the cultural and learning experience. Interactive and compelling exhibits, including two small exhibit theaters, and high-tech planetarium reveal stories of the Kumulipo, Hawaiian stories of origins, combined with origins and journeys of exploration by astronomers. Here, science and culture join together to inspire and offer a new perspective of seeing the world.

Laupahoehoe Train Museum and Visitor Center Located on highway 19, near mile marker 25 (look for the brown Hilo-Hamakua Heritage Coast signs and the railroad crossing signs in the front lawn). There's more than meets the eye. Housed in a beautifully restored railroad employee home, on the site of the old Laupahoehoe Train Station, furnished in the period of the early 1900’s. Public restrooms and Gift Shop available; on-going engine and caboose restorations on track.

A lesson in both cultural and natural history of Hawai‘i, the restored home of missionaries David and Sarah Lyman, built in 1839, houses Hawaiian, missionary and ethnic artifacts, volcano and mineral displays, flora and fauna, marine and land shells. Collections include Chinese and Hawaiian art, and features paintings and prints on the subject of Hawai‘i.

Pacific Tsunami Museum is a museum in Hilo, Hawaii dedicated to the history of the April 1, 1946 Pacific tsunami and the May 23, 1960 Chilean tsunami which devastated much of the east coast of the Big Island, especially Hilo. The museum also has a mission to educate people in general about tsunamis, including the 2004 Indian Ocean earthquake and tsunami. A scientific advisor to the museum has written a book on the two major disasters.

The observatory is managed by the U.S. Geological Survey, and the National Park Service. Its purpose is to study the activity of Mauna Loa and Kīlauea Volcanoes on a permanent, scientific basis. The Jaggar Museum contains numerous exhibits that explain the history and behavior of Hawaiian volcanoes.

The Observatories at Mauna Kea, (MKO), are an independent collection of astronomical research facilities located on the summit of Mauna Kea on the Big Island of Hawai'i, USA. The facilities are located in a 500-acre (2.0 km2) special land use zone known as the "Astronomy Precinct," which is located in the Mauna Kea Science Reserve. The Astronomy Precinct was established in 1967 and is located on land protected by the Historical Preservation Act for its significance to Hawaiian culture.

The Mokupapapa Discovery Center was constructed to interpret the natural science, culture, and history of the Northwestern Hawaiian Islands and surrounding marine environment. Interactive displays, engaging three-dimensional models, and immersive theater allow the visitor to experience the wonder and majesty of this special ocean region.